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This combination medication is employed to deal with signs of Parkinson's disease or symptoms that are parkinson-likesuch as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a substance that is naturally occurringdopamine) into the brain. Levodopa modifications into dopamine in mental performance, assisting to control movement. Carbidopa prevents the breakdown of levodopa in the bloodstream so more levodopa can enter mental performance. Carbidopa can also reduce some of levodopa's part effects such as for example vomiting and nausea.

Exactly how to use Sinemet

Take this medication by mouth with or without meals as directed by your doctor, often three or four times a day.

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Taking this medication with food might help to decrease nausea. It is best to avoid a diet that is high-proteinit decreases the amount of levodopa that your particular body takes in) during therapy, unless directed otherwise by your doctor. Separate your dosage with this medication by as many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your pharmacist or doctor for more details.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's directions carefully. This combination medication comes in various strengths with various amounts of carbidopa and levodopa in each tablet. Be sure you have the correct strength of both drugs. Your doctor could also alone prescribe carbidopa to be used with this combination.

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Utilize this medicine regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Some patients may experience a "wearing-off" (worsening of symptoms) prior to the next dose is due. An "on-off" effect may also happen, in which unexpected short periods of stiffness occur. If these effects occur, contact your physician for feasible dosage adjustments which will help to minimize this effect.

Do not stop taking this medication without consulting your physician. Some conditions could become even worse when this medication is quickly reduced or suddenly stopped. Your dose may need to be gradually reduced. (See also unwanted effects section.)

Tell your physician should your condition will not enhance or if it worsens.

Side Results

Dizziness, lightheadedness, nausea, vomiting, loss of appetite, trouble sleeping, uncommon dreams, or headache may occur. If some of these effects persist or worsen, tell your doctor or pharmacist immediately.

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This medication may cause saliva, urine, or sweat to turn a dark color. This impact is safe, however your clothes might be stained.

To lessen the risk of dizziness and lightheadedness, get right up slowly when increasing from a sitting or position that is lying.

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Remember that your doctor has prescribed this medicine she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have serious side effects.

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Some people taking this medication have fallen asleep suddenly during their usual daily activities (such as talking on the phone, driving). In some full cases, sleep occurred without any emotions of drowsiness ahead of time. This sleep impact may occur anytime during therapy with carbidopa/levodopa even if you used this medication for a long time. If you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities until you have discussed this effect with your doctor. Your risk with this sleep effect is increased by using liquor or other medications that will prompt you to drowsy. See also Precautions section.

Inform your doctor immediately if you have any serious side effects, including: new/worsening movements you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges).

Get medical help right away if you have any very serious side results, including: chest pain.

Abruptly stopping or reducing the dose of this medication may rarely cause an extremely condition that is serious neuroleptic malignant syndrome (NMS). Get medical help right away when you have any of the after symptoms: temperature, uncommon muscle tissue stiffness, severe confusion, perspiring, fast/irregular heartbeat, quick breathing.

a really serious reaction that is allergic this drug is rare. However, get help that is medical away in the event that you notice any observeable symptoms of a critical sensitive reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is perhaps not a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

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Phone your physician for medical advice about side-effects. You'll report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your medical practitioner for medical advice about side results. You may report side effects to Health Canada at 1-866-234-2345.

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Before using this medication, tell your doctor or pharmacist if you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergic reactions or other problems. Communicate with your pharmacist for lots more details.

Before applying this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, glaucoma, respiration issues (such as asthma), heart disease (such as for instance coronary arrest, irregular heartbeat), kidney disease, stomach/intestinal ulcer, mental/mood disorders (such as for instance depression, schizophrenia), blood problems, seizures, rest disorders.

This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit alcoholic beverages. See also Side Effects section.

Before having surgery, tell your doctor or dentist about all of the products you utilize (including prescription drugs, nonprescription drugs, and organic products).

During pregnancy, this medication should be utilized only when demonstrably required. Discuss the potential risks and benefits with your physician.

Levodopa passes into breast milk. It's unknown if carbidopa passes into breast milk. Check with your doctor before breast-feeding.

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