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See also Warning section.

Promethazine is utilized to avoid and treat nausea and vomiting related to certain conditions (such as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and nose that is runny. It may possibly be used to assist you feel sleepy/relaxed before and after surgery or even to help certain narcotic pain relievers (such as meperidine) work better. It may also be used for a short time to treat a runny nose due to the common cold.

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Promethazine is an antihistamine and works by blocking a particular natural substance (histamine) that the human body makes during an allergic reaction. Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other natural substances (such as for example acetylcholine) and by acting entirely on specific parts of mental performance.

Cough-and-cold items have not been shown to be effective or safe in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children more youthful than 6 years unless specifically directed by the doctor. Some items (such as long-acting tablets/capsules) are maybe not recommended for use in kids younger than 12 years. Pose a question to your doctor or pharmacist for more details about using your product safely.

These items never cure or shorten the size of the common cold and may cause serious side effects. To decrease the risk for serious side effects, follow all dosage carefully directions. Don't offer other medication that is cough-and-cold might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking fluids that are enough making use of a humidifier or saline nose drops/spray).

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Read the Patient Information Leaflet if available from your pharmacist before you start taking promethazine and each time you get a refill. If you have any relevant concerns, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, frequently 2 to 4 times daily. For motion sickness, the first dose of promethazine should be taken 30 to 60 minutes before beginning travel. For allergies, this medication may be taken once daily at bedtime to avoid drowsy that is being the afternoon. When used before surgery, promethazine may be taken the night before or just before the procedure and may be continued afterwards as directed.

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If you should be using the liquid form of this medication, carefully measure the dose using a measuring device/spoon that is special. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your age, medical condition, and response to treatment. In kids, the dosage may also be according to weight. Do not increase your dose and take this medication more often than directed.

Tell your doctor if your trouble does not enhance or if it worsens.

Side Impacts

Drowsiness, dizziness, constipation, blurred vision, or dry mouth may occur. If some of these results persist or worsen, tell your physician.

To relieve dry mouth, suck (sugarless) difficult candy or ice chips, chew (sugarless) gum, take in water, or use a saliva replacement.

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Remember that your physician has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately in the event that you have any serious side-effects, including: fainting, slow heartbeat, mental/mood changes (such as hallucinations, nervousness, irritability, restlessness, confusion), unusual/uncontrolled movements (such as fixed upward stare, neck twisting, tongue movements), shaking (tremor), difficulty urinating, easy bleeding/bruising, signs of infection (such as fever, persistent sore neck), severe stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes/skin.

Get help that is medical away if you have any very severe side effects, including: slow/shallow breathing, seizures.

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This medication may rarely cause a very condition that is serious neuroleptic malignant syndrome (NMS). Get help that is medical away if you've got any of the after symptoms: temperature, muscle stiffness/pain/tenderness/weakness, severe tiredness, serious confusion, sweating, fast/irregular heartbeat, dark urine, change in the amount of urine.

A very serious reaction that is allergic this drug is rare. However, get help that is medical away in the event that you notice any outward symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing.

That is not a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Phone your doctor for medical advice about part results. You may report side effects to Food And Drug Administration at 1-800-FDA-1088 or at

In Canada - Phone your doctor for medical advice about side impacts. You may report effects that are side Health Canada at 1-866-234-2345.


See section that is also warning.

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Before taking promethazine, tell your doctor or pharmacist in the event that you have any other allergies if you are allergic to it; or to any other phenothiazines (such as prochlorperazine); or. This product may contain ingredients that are inactive which may cause allergic reactions or other problems. Communicate with your pharmacist to get more details.

Before making use of this medicine, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, chronic obstructive pulmonary disease-COPD, sleep apnea), blood/immune system dilemmas (such as bone marrow depression), high force within the attention (glaucoma), heart problems (such as irregular heartbeat), high bloodstream pressure, liver illness, specific brain disorders (such as neuroleptic malignant problem, Reye's syndrome, seizures), stomach/intestine problems (such as for instance blockage, ulcer), overactive thyroid (hyperthyroidism), difficulty urinating (for example, due to enlarged prostate).

This drug may allow you to be dizzy or drowsy or cause vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Avoid alcoholic beverages.

Before having surgery, tell your medical practitioner or dentist about all these products you use (including prescription drugs, nonprescription medications, and herbal products).

Promethazine may make you more responsive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Make use of a sunscreen and wear protective clothing when out-of-doors.

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This medicine might make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. Once the weather is hot, take in a complete lot of fluids and dress lightly. If you overheat, quickly look for a accepted place to cool down and sleep. Get help that is medical away for those who have a fever that does not disappear, mental/mood changes, hassle, or dizziness.

Liquid products may contain sugar and/or alcohol. Caution is preferred you to limit/avoid these substances in your diet if you have diabetes, liver disease, or any other condition that requires. Ask your doctor or pharmacist about using this item safely.

Children may be more painful and sensitive to the side effects of this drug, particularly slowed respiration (see alert part). This drug can cause excitement in often young children instead of drowsiness. Special care should be taken when using this medication in children who have lost a complete lot of fluid (dehydration), people who have actually a household history of unexpected infant death syndrome (SIDS), and those who are difficult to wake up from sleep.

Older grownups may be more sensitive to the relative part effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling.

During maternity, this medicine should be used only when demonstrably needed. Discuss the risks and advantages together with your doctor.

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It is unknown if promethazine passes into breast milk. It might probably have effects that are undesirable a nursing infant. Consult your doctor before breast-feeding.

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