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Uses

This medication is utilized to treat movement problems caused by Parkinson's disease. It does not cure Parkinson's disease, however it may improve shakiness (tremor), muscle stiffness, loss of normal motion as your dose of other Parkinson's medication wears down (end-of-dose failure), and sudden switching between normal movement and stiffness ("on-off" problems). It may enhance your range of motion and ability to walk, dress, and exercise. Selegiline is usually used in combination with other medicines (e.g., levodopa, carbidopa).

Selegiline is an enzyme blocker (MAO inhibitor) that works by slowing the breakdown of particular natural substances in the brain (neurotransmitters such as for instance dopamine, norepinephrine, and serotonin).

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Take this medication by mouth, usually twice daily with breakfast and lunch. Taking selegiline late in the may cause trouble sleeping day. Dosage is based on your condition that is medical and to therapy. Do not increase your dose or take it more often than directed.

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You to lower your levodopa dose after you have been taking selegiline for 2 or 3 days, your doctor may direct. Follow your medical professional's instructions closely. Usually do not stop or change the dose of any of your medications without first talking along with your doctor.

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It would likely take a few weeks for the full great things about the drug to be noticed. Do not stop taking this drug without first consulting your doctor. Talk to your medical practitioner if the medication stops working well or if your condition worsens.

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Side Effects

Dizziness, abdominal pain, dry lips, sickness, stomach upset, difficulty sleeping, and headache might occur. If some of these effects persist or worsen, notify your doctor or pharmacist promptly.

If you are also taking levodopa, you may experience more side effects from the levodopa when taking selegiline. Tell your doctor right away if any of these side effects occur: nausea, shakiness, muscle stiffness, mental/mood changes such as hallucinations/abnormal dreams. Your doctor may need to change your medication or dose. Don't stop or change the dose of your levodopa without talking with your physician first.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have side that is serious.

Some people taking selegiline have fallen asleep suddenly during their usual daily activities (such as talking on the phone, driving). In some full cases, sleep occurred without any emotions of drowsiness beforehand. This sleep effect might occur anytime during therapy with selegiline even although you have used this medication for a time that is long. Until you have discussed this effect with your doctor if you experience increased sleepiness or fall asleep during the day, do not drive or take part in other possibly dangerous activities. Your risk of this sleep effect is increased by using liquor or other medications that can cause you to drowsy. See also Precautions section.

Tell your doctor right away for those who have any side that is serious, including: fainting, loss in balance, mental/mood changes (age.g., agitation, confusion, depression, hallucinations), unusual strong urges (such as increased gambling, increased intimate urges), worsening muscle stiffness/twitching, changes in sexual ability/interest, increased shaking (tremor), distended ankles/legs, difficulty urinating, uncommon weight gain, simple bleeding/bruising, black/tarry stools, vomit that looks like coffee grounds.

This drug may rarely cause an attack of extremely high blood pressure (hypertensive crisis), which may be fatal. Many food and drug interactions can increase this risk. (See also Drug Interactions section.) Get medical help right away if any of these serious side-effects occur: frequent/severe headache, fast/slow/irregular/pounding heartbeat, chest discomfort, neck stiffness/soreness, serious nausea/vomiting, sweating/clammy skin (sometimes with fever), widened pupils, vision changes (age.g., double/blurred vision), sudden sensitivity to light (photophobia).

This medicine may increase serotonin and rarely cause an extremely serious condition called serotonin syndrome. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away if you develop some associated with after symptoms: hallucinations, unusual restlessness, loss in coordination, fast heartbeat, severe dizziness, unexplained temperature, severe nausea/vomiting/diarrhea, twitching muscle.

A tremendously serious allergic reaction to this drug is rare. However, get medical help right away if you notice any observeable symptoms of a severe allergic attack, including: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble respiration.

This just isn't a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

Phone your medical professional for medical advice about side-effects. You may report effects that are side Food And Drug Administration at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Phone your physician for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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Precautions

Before taking selegiline, tell your medical professional or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which causes allergic reactions or other problems. Talk to your pharmacist to get more details.

Before using this medication, tell your physician or pharmacist your medical history, especially of: a certain type of adrenal gland tumor (pheochromocytoma), cerebrovascular disease (e.g., stroke), heart disease (e.g., congestive heart failure, coronary arrest), bleeding problems, history of severe/frequent headaches, peptic ulcer, diabetes, personal/family history of mental/mood disorders (e.g., schizophrenia, bipolar disorder), personal/family reputation for high blood pressure, liver condition, overactive thyroid (hyperthyroidism).

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This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit beverages that are alcoholic. See also Side Effects section.

To reduce dizziness plus the danger of fainting, get up slowly when rising from a sitting or lying position.

Before having surgery, tell your dentist or doctor you are taking this medication. You might have to stop taking this drug beforehand. Follow your physician's instructions carefully.

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Selegiline is used only when clearly needed during pregnancy. Discuss the potential risks and benefits along with your doctor.

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It's not known if this medication passes into breast milk. Consult your physician before breast-feeding.

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