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See section that is also warning.

This medication is used to take care of mental/mood that is certain (schizophrenia, schizoaffective disorders). Clozapine is a medication that is psychiatricanti-psychotic type) that actually works by helping to restore the balance of certain natural substances (neurotransmitters) within the brain.

Clozapine decreases hallucinations and helps prevent committing suicide in individuals who are most likely to use to harm themselves. It will help one to think more clearly and definitely about your self, feel less nervous, and be a part of everyday life.

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If you are utilising the liquid form of this medication, read the Patient Information Leaflet if available from your pharmacist before you start taking clozapine and each time you get a refill. For those who have any relevant concerns, pose a question to your doctor or pharmacist.

Simply take this medicine by mouth with or without food, as directed by your doctor. If you're taking the pills that dissolve in the lips, remove each tablet carefully from the blister pack immediately before taking your dose. Allow the tablets to dissolve on your swallow and tongue. There is no need to take the dissolving tablets with water. Discard any dissolving tablets that are previously exposed to air due to opened/damaged packaging. Do not save your self them for your following dose.

If you work with the form that is liquid of medication, shake the bottle well for 10 seconds before each use. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you might not obtain the correct dose.

You should begin taking this drug at a dose that is low increasing your dose slowly, to lessen side effects such as dizziness, drowsiness and seizures. Follow your doctor's instructions exactly. Your dosage is based on your medical condition and response to treatment. Since clozapine can cause a decrease in white blood cells, you will need to get blood tests done regularly as directed. Be sure to keep all appointments of these laboratory tests. (See also Notes section.)

You were on (see Missed Dose section) if you miss your doses for longer than a day or two, consult your doctor for a new schedule to get back to the dose. Use this medication regularly in order to get the most benefit from it. To greatly help you keep in mind, use it at the time( that is same) each day.

Do not stop taking clozapine without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Also, you may experience symptoms such as severe sweating, headache, sickness, vomiting, and diarrhea. To prevent these signs while you're stopping treatment with this drug, your medical professional may lower your dosage slowly. Consult your doctor or pharmacist for more details. Report any new or symptoms that are worsening away.

It usually takes many weeks prior to the full benefit of this medication takes effect. Inform your doctor if the condition persists or worsens.

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Part Effects

See also Warning section.

Drooling, drowsiness, dizziness, headache, shaking tremor that is(, vision problems (e.g., blurred vision), weight gain, and constipation may occur. Many of these effects (especially drowsiness) lessen as your body gets used to the medication. If any of these effects persist or worsen, contact your pharmacist or doctor quickly.

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To avoid constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. If you feel constipated when using this medication, consult with your pharmacist for help in selecting a laxative (e.g., stimulant-type with stool softener).

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Keep in mind that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have side that is serious.

This medication may rarely make your blood sugar level rise, which can cause or worsen diabetes. Rarely, very serious conditions such as diabetic coma may occur. Tell your physician immediately if you develop symptoms of high blood sugar levels, such as increased thirst and urination. If you already have diabetic issues, be sure to check your bloodstream sugars regularly. Your medical professional may need to adjust your diabetes medication, exercise program, or diet.

This medication could also cause weight that is significant and a growth in your cholesterol (or triglyceride) levels. These effects, along with diabetes, may increase your risk for developing heart condition. Discuss the dangers and benefits of treatment with your medical practitioner.

Tell your doctor right away for those who have any serious side effects, including: facial/muscle twitching, seizures, uncontrollable movements.

Get help that is medical away if you have any really severe part effects, including: severe dizziness, fainting, mental/mood changes, trouble respiration with exercise, sudden weakness, pain/redness/swelling of the arms/legs, persistent nausea/vomiting, stomach/abdominal pain, yellowing of eyes/skin.

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This medicine may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). Get help that is medical away if you have any associated with the following symptoms: temperature, muscle mass stiffness/pain/tenderness/weakness, severe tiredness, serious confusion, sweating, fast/irregular heartbeat, dark urine, change in the number of urine.

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A really severe reaction that is allergic this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic add: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This isn't a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your physician for medical advice about part effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You might report side effects to Health Canada at 1-866-234-2345.


See also Warning and Side Effects sections.

Before taking clozapine, inform your doctor or pharmacist in the event that you have any other allergies if you are allergic to it or. This product may contain inactive ingredients, which trigger allergic reactions or other dilemmas. Speak to your pharmacist for more information.

Before using this medicine, tell your physician or pharmacist your medical history, especially of: history of blood disorders (such as leukemia, low blood that is white count), bowel problems (such as paralytic ileus, irritable bowel problem ), breathing problems, diabetes/family history of diabetes, high cholesterol/triglyceride levels, glaucoma, heart problems, kidney problems, liver problems, obesity/family history of obesity, seizures, difficulty urinating (such as prostate problems).

Clozapine may cause an ailment that impacts the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely deadly) fast/irregular heartbeat and other signs (such as for instance severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased when you yourself have particular medical conditions or are taking other drugs which could affect the heart rhythm. Before utilizing clozapine, tell your medical professional or pharmacist of all of the the drugs you take and when you yourself have some of the following conditions: certain heart problems (heart failure, sluggish heartbeat, QT prolongation in the EKG), genealogy and family history of certain heart disease (QT prolongation into the EKG, unexpected cardiac death).

Lower levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your doctor about making use of clozapine safely.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit beverages that are alcoholic.

Tell your medical professional because you may be at a higher risk for a drop in your white blood cells if you are a descendent of Ashkenazi Jews.

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Before having surgery, tell your doctor or dentist that you're by using this medication.

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Liquid services and products or dissolving tablets may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is encouraged you to limit/avoid these substances in your diet if you have diabetes, liver disease, phenylketonuria (PKU), or any other condition that requires. Ask your pharmacist or doctor about applying this product safely.

Older grownups may be more sensitive to the relative part ramifications of this drug, specially constipation, dizziness, and QT prolongation (see above). Dizziness can raise the danger of falling.

During maternity, this medicine should be used only when plainly needed. Babies born to moms who have used this drug over the past 3 months of maternity may rarely develop signs including muscle stiffness or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. If you notice any of these symptoms in your newborn especially during their month that is first the doctor right away.

Since untreated mental/mood issues (such as schizophrenia, schizoaffective problems) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This medicine may pass into breast milk and have now undesirable effects on a nursing infant. Breast feeding is not advised while taking clozapine. Consult your physician before breast-feeding.

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