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Clomipramine is used to take care of obsessive disorder that is compulsiveOCD). It helps decrease persistent/unwanted thoughts (obsessions), and it assists in easing the urge to perform duplicated tasks (compulsions such as hand-washing, counting, checking) that interfere with day to day living.

This medication belongs to a course of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, amongst others) in the mind.

DIFFERENT USES: This area contains uses of this drug that are perhaps not listed in the approved labeling that is professional the drug but that could be prescribed by your medical care professional. Use this medication for a condition that is detailed in this part only if it has been so prescribed by your health care professional.

This medication has additionally been used to treat depression, panic assaults, and pain that is ongoing.

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Read the Medication Guide available from your own pharmacist. Consult your doctor or pharmacist if you have any concerns.

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Take this medication by mouth with or without meals as directed by your physician. To minimize side-effects such as stomach upset, clomipramine may be started at a low dose, given in several doses during the day with meals, and slowly increased as your body gets used to it. After you have reached the best dose for you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor. Often, the daily dose will maybe not be more than 250 milligrams for grownups and 200 milligrams for kids and teenagers.

Follow your physician's directions very carefully. Usually do not take just about medication or take it more frequently than prescribed. Your condition shall not improve any faster and your risk of side results such as seizures may be increased. Dosage is founded on your medical condition and response to therapy.

Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more information.

Make use of this medication regularly in order to obtain the most benefit from it. Continue to take it even if you feel well. To help you remember, use it at the same time(s) each time.

Usually do not suddenly stop taking this medication without consulting your doctor. Some conditions may be worse when the drug is abruptly stopped. You may possibly experience sweating, dizziness, nausea, vomiting, headache, or irritability if you instantly stop using this drug. Your dose may need to be gradually decreased.

It might just take 2 to 3 weeks or longer ahead of the full effects of this medication are noticed. Inform your physician if the condition persists or if it worsens.

Side Effects

See section that is also warning.

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Dizziness, drowsiness, dry lips, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety symptoms may temporarily aggravate when you initially start clomipramine that is taking. If any of these effects persist or worsen, notify your pharmacist or doctor promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or use a saliva substitute.

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To stop constipation, maintain a diet adequate in fiber, drink plenty of water, and workout. If you become constipated while using this drug, check with your pharmacist for aid in selecting a laxative (age.g., stimulant-type with stool softener).

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your physician right away if any of these unlikely but serious side effects happen: mental/mood changes (e.g., confusion, depression, memory problems), enlarged/painful breasts, unwanted breast milk manufacturing, irregular/painful menstrual durations, muscle tissue stiffness, ringing within the ears, sexual issues (e.g., reduced sexual ability, changes in desire), shakiness (tremors), numbness/tingling associated with the hands/feet, trouble urinating.

Tell your physician straight away if any of these rare but really side that is serious occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled motions (especially associated with tongue/face/lips), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and hardly ever cause a very condition that is serious serotonin syndrome/toxicity. The risk increases you take if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away if you develop a few of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscle tissue, unexplained fever, uncommon agitation/restlessness.

Get help that is medical away in the event that you have any very severe side effects, including: black stools, chest pain, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision modifications (such as seeing rainbows around lights at night).

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A very severe allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially regarding the face/tongue/throat), severe dizziness, trouble breathing.

It is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Call your physician for medical advice about side effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side-effects. You could report side effects to Health Canada at 1-866-234-2345.


Before taking clomipramine, tell your doctor or pharmacist if you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or. This product may contain ingredients that are inactive which can cause allergic reactions or other dilemmas. Talk to your pharmacist for more information.

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Before using this medication, tell your doctor or pharmacist your health background, especially of: blood dilemmas (e.g., purpura, thrombocytopenia), difficulty in breathing (e.g., asthma, chronic bronchitis), personal or family history of glaucoma (angle-closure type), eating disorders (age.g., bulimia), heart dilemmas (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal issues (e.g., chronic constipation, ileus), liver problems, renal dilemmas, personal or family history of other mental/mood conditions (e.g., bipolar disorder, schizophrenia), history of hospitalization for a very severe response to specific medicines (neuroleptic malignant syndrome), heartburn/stomach acid within the esophagus (age.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may increase your threat of seizures (e.g., alcohol/sedative dependency, usage of electroconvulsive therapy, mind injury/disease), specific types of tumors (e.g., pheochromocytoma, neuroblastoma).

Clomipramine may cause a disorder that affects the heart rhythm (QT prolongation). QT prolongation can seldom cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical help straight away.

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The danger of QT prolongation can be increased in the event that you have actually certain medical conditions or are using other drugs that might cause QT prolongation. Before using clomipramine, tell your medical professional or pharmacist of all drugs you take of course you have got any of the next conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family reputation for certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Lower levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your physician about making use of clomipramine safely.

This drug may make you dizzy or drowsy or cause temporary vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

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To decrease dizziness and lightheadedness, get up slowly when increasing from a seated or lying position.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Caution is recommended when using this drug in kids who participate in active activities as it might increase the risk of heart problems. (See also the Warning section.)

Older adults may be more sensitive to your relative negative effects of this medication, especially bleeding, confusion, dizziness, and QT prolongation (see above).

This medication should be used only when obviously needed during pregnancy. Newborns exposed to clomipramine during pregnancy might experience withdrawal symptoms or side effects. Tell your doctor right away if you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.

Since untreated mental/mood dilemmas (such as for example obsessive disorder that is compulsive depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.

This drug passes into breast milk and could have undesirable effects on a nursing baby. Consult your doctor before breast-feeding.

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