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This medication is utilized to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum may lead to acne that is severe. If left untreated, severe acne may cause scarring that is permanent.

DIFFERENT USES: This area contains uses of this drug which can be not detailed in the approved labeling that is professional the drug but that could be prescribed by your wellbeing care pro. Make use of this drug for a state of being which is listed in this section as long as it has been so prescribed by your wellness care professional.

This medicine may also be used to deal with a certain type of cancer (neuroblastoma).

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Read the Medication Guide supplied by your pharmacist before you start using isotretinoin and each time you get a refill. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions about isotretinoin, consult your physician or pharmacist before taking the medication.

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Swallow capsules whole. Usually do not crush or chew them. Isotretinoin is usually taken twice daily for 15-20 weeks, or as directed by your physician. Directions for most generic forms of isotretinoin state that it is taken with meals. Nevertheless, the FDA has indicated that the Absorica brand might be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your doctor or pharmacist to get more information. Take this drug with a glass that is full of, and do not lie down for 10 mins after taking it.

The dosage is based on your medical condition, weight, and reaction to treatment.

Your acne may worsen throughout the first day or two of taking this medication, plus it may occupy to 1-2 months before you notice the full benefit of this medication. If severe acne returns, a second course of treatment may be started after you have stopped taking the drug for 2 months. The manufacturer doesn't recommend long-term use of isotretinoin. Never take more than the recommended dose.

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Since this drug could be consumed through the skin and lungs and may harm an baby that is unborn women who are pregnant or who may become pregnant should not handle this medicine or inhale the dust from the capsules.

Negative Effects

Dry lips and mouth, minor inflammation of the eyelids or lips, crusty epidermis, nosebleeds, upset stomach, or thinning of hair may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice potato chips, chew (sugarless) gum, drink water, or utilize a saliva substitute.

Remember that the medical practitioner has recommended this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have side that is serious.

Tell your physician right away if you have actually some of these unlikely but side that is serious: mental/mood changes (e.g., depression, aggressive or violent behavior, plus in uncommon cases, thoughts of committing suicide), tingling feeling in the skin, quick/severe sunburn (sun sensitivity), back/joint/muscle pain, signs of infection (age.g., fever, persistent sore throat), painful swallowing, peeling epidermis on palms/soles.

Isotretinoin may seldom cause disease regarding the pancreas (pancreatitis) that may seldom be fatal. Stop taking this medication and inform your physician right away if you develop: severe stomach pain, serious or nausea/vomiting that is persistent.

Stop using this medication and tell your doctor right away if you develop these not likely but very serious side effects: serious hassle, vision modifications, tinnitus, hearing loss, chest pain, yellowing eyes/skin, dark urine, severe diarrhoea, rectal blood.

A very serious reaction that is allergic this drug is rare. However, seek immediate medical attention if you notice any outward symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

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This just isn't a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Within the US -

Phone your doctor for medical advice about negative effects. You might report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your medical professional for medical advice about side effects. You may report effects that are side wellness Canada at 1-866-234-2345.


Before taking isotretinoin, tell your doctor or pharmacist in the event that you have any other allergies if you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or. This product may contain inactive ingredients (such as soybean, parabens), which can cause allergic reactions or other dilemmas. Some those who are sensitive to peanuts may be allergic to also soy. Speak to your pharmacist for more information.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders (e.g., anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density).

Do not donate bloodstream while you are taking isotretinoin and for at least 1 month after you stop taking it.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when in the open air.

Isotretinoin can impact your night vision. Do not drive, use machinery, or do any activity that requires clear vision after dark you can perform such activities safely until you are sure.

If you wear contact lenses, you may not tolerate them as well as usual while using this medication. Contact your doctor for lots more information.

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Do not have procedures that are cosmetic smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring may occur.

Avoid the application of alcohol while taking this medication because it might increase the possibility of certain negative effects (e.g., pancreatitis).

Restricted information suggests isotretinoin might cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop normal growth in some children (epiphyseal plate closing). Consult your physician for more details.

Care is preferred when utilizing this medication within the elderly because they may be more delicate to its effects, especially the effects on bones.

Caution is advised when working with this drug in young ones because they might be more responsive to its impacts, especially back/joint/muscle pain.

This drug must not be used during pregnancy or by those who may become pregnant during treatment. You may be pregnant, inform your doctor right away if you become pregnant or think. See section that is also warning.

Since this drug is absorbed through skin and lungs and may harm an unborn baby, women who are pregnant or who may become expecting must not handle this medicine or breathe the dust from the capsules.

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You must have two negative pregnancy tests before starting this medication. You must have a pregnancy that is monthly during treatment with isotretinoin. If the test is good, you must stop taking this medication and consult your medical practitioner right away.

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Its unknown if this medication passes into breast milk. However, similar medications pass into breast milk. Breast-feeding while by using this drug is not advised. Consult your medical practitioner before breast-feeding.

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